If you’re looking into peptides for weight loss, you might be wondering what retatrutide is and how the dosage works and what to expect.
This new treatment is gaining attention for its results, but knowing how to dose it properly can make all the difference in your success and comfort.
At Gard Wellness Solutions, we help guide people through personalized weight loss plans that include medications like retatrutide.
Let’s break down everything you need to know about retatrutide dosage, from the basics to what happens week by week.
What Is Retatrutide?
Retatrutide is a type of medication that activates three hormone receptors—GLP-1, GIP, and glucagon.
These hormones work together to help reduce appetite, improve how your body uses energy, and support steady weight loss.
What sets retatrutide apart is how it combines multiple mechanisms into one injection.
That means better control over hunger, better fat burning, and, for many people, greater overall weight loss results.
The Recommended Retatrutide Dosage Schedule
When starting retatrutide, the key is to begin with a small dose and gradually increase it.
This step-by-step approach helps your body adjust and makes it easier to manage any side effects.
Here’s a typical weekly retatrutide titration schedule:
- Weeks 1 to 2: 1 mg once a week
- Weeks 3 to 4: 2 mg once a week
- Weeks 5 to 8: 4 mg once a week
- Weeks 9 to 12: 8 mg once a week
- Week 13 and beyond: 12 mg once a week
Not everyone follows the exact same schedule.
Some people stay on lower doses longer, especially if they’re more sensitive or experience side effects.
At Gard Wellness Solutions, we help adjust the plan based on how your body responds.
What Clinical Studies Say About Dosage
One of the biggest studies on retatrutide found that people lost up to 24.2% of their body weight after 48 weeks.
Those taking higher doses, like 8 mg and 12 mg, saw the most weight loss.
That said, even lower doses showed noticeable results over time.
The research also showed that most side effects were related to the speed of dose increases.
That’s why we take a gradual approach when building your plan—slow and steady tends to work best.
Retatrutide Dosage Chart
To make it easier to see how the dosage progresses, here’s a simplified chart:
| Week | Dose | What to Expect |
| 1–2 | 1 mg | Helps your body adjust |
| 3–4 | 2 mg | Hunger begins to decrease |
| 5–8 | 4 mg | Early signs of weight loss |
| 9–12 | 8 mg | Fat loss becomes noticeable |
| 13+ | 12 mg | Full-strength benefits for ongoing results |
This is just a guide.
We’ll work with you to adjust it based on your experience and goals.
How to Manage Retatrutide Side Effects
It’s normal to have some side effects when you start a new weight loss medication.
With retatrutide, the most common ones include nausea, bloating, or digestive issues.
These usually happen during the first few weeks or when increasing your dose.
At Gard Wellness Solutions, we check in with you regularly and make small changes to your plan if needed.
If side effects show up, we can slow down your titration schedule or give you tips to stay hydrated and eat in a way that supports your comfort.
Who Should Consider Retatrutide?
Retatrutide may be a good option if you’ve tried diet and exercise and still find weight loss difficult.
It’s especially helpful for people with a higher body mass index or those struggling with weight-related health concerns.
We’ll walk you through a full evaluation before starting.
That way, you’ll know whether retatrutide is a fit for you and how we can tailor the plan to your specific needs.
How Gard Wellness Solutions Can Help With Retatrutide Dosage
At Gard Wellness Solutions, we personalize every part of your care.
If retatrutide is right for you, we’ll create a clear, step-by-step dosage plan that fits your body and lifestyle.
We also offer:
- One-on-one support with medical professionals who understand how to manage weight loss safely
- Guidance on nutrition, habits, and mindset to keep your progress steady
- Easy access to weight loss treatments, including retatrutide
If you’re ready to take the next step, you can learn more about retatrutide through our dedicated page or set up a consultation with us.
How to Get Started with Retatrutide
Here’s how it works when you begin a retatrutide plan with us:
- We meet with you for a detailed consultation and review your health history.
- We discuss your goals and explain how retatrutide works.
- You’ll receive lab testing and a customized dosage schedule.
- We check in weekly or bi-weekly to monitor your results and help manage any side effects.
This approach helps you feel supported from day one and keeps things moving in the right direction.
Conclusion: Retatrutide Dosage
When used correctly, the right retatrutide dosage can lead to real, lasting weight loss.
The key is knowing how to increase your dose at the right pace and working with a team that knows how to guide you through the process.
At Gard Wellness Solutions, we’re here to help you every step of the way.
From your first appointment to your maintenance phase, we’ll make sure your plan is working for your body, your lifestyle, and your goals.
Let us help you take the guesswork out of weight loss—and make your progress feel possible again.
FAQs: Retatrutide Dosage
What are the benefits of retatrutide vs semaglutide?
Retatrutide targets three hormone receptors—GLP-1, GIP, and glucagon—while semaglutide only targets GLP-1. This multi-receptor approach may lead to greater appetite control, increased fat burning, and potentially more weight loss over time compared to semaglutide alone.
What are the benefits of retatrutide vs tirzepatide?
Tirzepatide works on two receptors (GLP-1 and GIP), while retatrutide works on three, adding glucagon receptor activation. This added mechanism may support faster fat loss, better metabolic function, and potentially improved results for people with obesity or insulin resistance.
Is retatrutide the same as Ozempic?
No, retatrutide is not the same as Ozempic. Ozempic contains semaglutide, which only activates the GLP-1 receptor. Retatrutide activates GLP-1, GIP, and glucagon receptors, offering a broader approach to weight loss and metabolic health.
How fast do you lose weight on retatrutide?
Many people start to see weight loss within the first 4 to 8 weeks, especially as they move into higher doses. In clinical studies, significant weight loss was observed around the 24-week mark, with continued progress through 48 weeks.
How long do you stay on retatrutide?
The length of treatment varies based on your goals and how your body responds. Some people stay on retatrutide for several months, while others may continue longer to maintain their results. We tailor the plan to your specific needs.
Does retatrutide increase metabolism?
Retatrutide may help improve metabolic function by increasing energy use and supporting fat breakdown through its action on the glucagon receptor. While not a direct stimulant, it may contribute to a more efficient metabolism over time.
